Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 8/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28887474 | 0.90 | TSHR (0.44) | TSHRALDH1A1FDPSGGPS1 | |
| SCHEMBL11785952 | 0.86 | TSHR (0.37) | SMN1; SMN2TSHRLMNAALDH1A1FDPS | |
| SCHEMBL4623887 | 0.86 | TSHR (0.44) | TSHRALDH1A1FDPSGGPS1 | |
| SCHEMBL8993592 | 0.86 | TSHR (0.40) | TSHRALDH1A1FDPSGGPS1 | |
| SCHEMBL8037301 | 0.83 | TSHR (0.34) | TSHRALDH1A1FDPSGGPS1 | |
| SCHEMBL11055615 | 0.81 | TSHR (0.40) | TSHRALDH1A1FDPSGGPS1 | |
| SCHEMBL28888935 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL28597575 | 0.79 | LMNA (0.50) | SMN1; SMN2TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL28368996 | 0.79 | LMNA (0.50) | SMN1; SMN2TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL15016234 | 0.79 | LMNA (0.50) | SMN1; SMN2TSHRLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428286-A2 | 24- and 25-substituted avermectin and milbemycin derivatives | MERCK & CO. INC. (US) | 1991-05-22 | — | — | EP | disclosed |