Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL936385 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL6730524 | 0.93 | NAPRT (0.60) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL360206 | 0.90 | NAPRT (0.56) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL29133271 | 0.90 | NAPRT (0.56) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL4636073 | 0.89 | — | — | |
| Pyridine SCHEMBL8916332 | 0.88 | NAPRT (0.53) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL27310910 | 0.88 | NAPRT (0.53) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL367908 | 0.88 | NAPRT (0.53) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL27894846 | 0.87 | NAPRT (0.60) | NAPRTTSHRTDP1KMT2AMEN1 | |
| Pyridine SCHEMBL5278800 | 0.86 | NAPRT (0.69) | NAPRTTSHRTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438795-A1 | Pyridine-2,4- and 2,5-dicarboxydi(nitroxyalkyl)amides, processes for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-31 | — | — | EP | disclosed |