Pyridine

Pyridine

SCHEMBL8916332

NC(=O)Cl.c1ccncc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 4/20 0.53
TSHR P16473 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
F7 P08709 1/20 0.39
F3 P13726 1/20 0.39
SARM1 Q6SZW1 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.39
SIRT6 Q8N6T7 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
SIRT3 Q9NTG7 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39
SIRT4 Q9Y6E7 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 2/20 0.36
APP P05067 1/20 0.36
GAA P10253 1/20 0.36
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL936385 0.88 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL1070164 0.88 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL6730524 0.88 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL1164077 0.88 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL9851406 0.88 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL9065525 0.88 NAPRT (0.60) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL29133271 0.85 NAPRT (0.56) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL28762998 0.85 NAPRT (0.56) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL360206 0.85 NAPRT (0.56) NAPRTTSHRTDP1F7F3
Pyridine SCHEMBL27643283 0.85 NAPRT (0.56) NAPRTTSHRTDP1F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5601971-A HIGH STRENGTH, WATERPROOF; CONTAINING AN IMIDAZOLIUM AND A S-TRIAZINE COMPOUND STERLING DIAGNSOTIC IMAGING, INC. (US) 1997-02-11 US disclosed