Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704704 | 0.95 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9851461 | 0.88 | AGTR1 (0.45) | PPARGAGTR1AGTR2 | |
| SCHEMBL9851509 | 0.86 | AGTR1 (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL8972048 | 0.85 | AGTR1 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL9851447 | 0.85 | PPARG (0.50) | PPARGAGTR1AGTR2 | |
| SCHEMBL9851517 | 0.84 | AGTR1 (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9851496 | 0.84 | PPARG (0.51) | PPARGAGTR1 | |
| SCHEMBL9851474 | 0.83 | AGTR1 (0.50) | PPARGAGTR1AGTR2 | |
| SCHEMBL9194632 | 0.82 | PPARG (0.62) | PPARGAGTR1AGTR2 | |
| SCHEMBL9705276 | 0.81 | AGTR1 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |