Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851577 | 0.85 | KDM4E (0.40) | KDM4ELMNAMAPK1NPSR1 | |
| SCHEMBL9851591 | 0.81 | TSHR (0.36) | TSHR | |
| SCHEMBL9851614 | 0.80 | CYP2D6 (0.36) | TSHR | |
| Bromide SCHEMBL9851562 | 0.79 | TSHR (0.35) | TSHR | |
| SCHEMBL24137999 | 0.79 | KDM4E (0.47) | KDM4EGAATSHRLMNAMAPK1 | |
| SCHEMBL10646186 | 0.74 | KDM4E (0.33) | KDM4EGAA | |
| SCHEMBL10238594 | 0.74 | KDM4E (0.40) | KDM4EGAATSHR | |
| SCHEMBL18415192 | 0.73 | GAA (0.43) | KDM4EGAALMNAMAPK1 | |
| SCHEMBL25511995 | 0.72 | GAA (0.42) | KDM4EGAATSHRLMNAMAPK1 | |
| SCHEMBL4078203 | 0.71 | GAA (0.34) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417631-A2 | Condensed diazepinones, process for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1991-03-20 | — | — | EP | disclosed |