Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851573 | 0.85 | KDM4E (0.37) | KDM4ELMNAMAPK1NPSR1 | |
| SCHEMBL9851593 | 0.82 | S1PR4 (0.30) | KDM4ES1PR4S1PR1S1PR3S1PR5 | |
| Bromide SCHEMBL9851723 | 0.81 | — | — | |
| SCHEMBL9851614 | 0.77 | CYP2D6 (0.36) | — | |
| SCHEMBL24670563 | 0.76 | KDM4E (0.37) | KDM4E | |
| SCHEMBL23900335 | 0.74 | KDM4E (0.45) | KDM4ES1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL4078203 | 0.72 | GAA (0.34) | KDM4EKMT2A | |
| SCHEMBL24137999 | 0.68 | KDM4E (0.47) | KDM4ELMNAMAPK1NPSR1KMT2A | |
| SCHEMBL24960426 | 0.67 | HRH2 (0.41) | KDM4ES1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL27393425 | 0.67 | HRH2 (0.41) | KDM4ES1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417631-A2 | Condensed diazepinones, process for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1991-03-20 | — | — | EP | disclosed |