SCHEMBL9851598

SCHEMBL9851598

CN1CCC(CBr)(CBr)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9060316 0.77 OPRM1 (0.34) DRD4OPRM1
SCHEMBL18821693 0.75 DRD4 (0.33) DRD4OPRM1
SCHEMBL9851667 0.75 DRD4 (0.33) DRD4OPRM1
SCHEMBL15026989 0.73 DRD4 (0.32) DRD4OPRM1
SCHEMBL25501484 0.70
SCHEMBL23466106 0.70 DRD4 (0.31) DRD4OPRM1
SCHEMBL15027014 0.70 DRD4 (0.31) DRD4OPRM1
SCHEMBL20104170 0.70 DRD4 (0.31) DRD4OPRM1
SCHEMBL14431981 0.70 DRD4 (0.31) DRD4OPRM1
SCHEMBL15601421 0.70 DRD4 (0.34) DRD4OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417631-A2 Condensed diazepinones, process for their preparation, and medicaments containing these compounds Dr. Karl Thomae GmbH (DE) 1991-03-20 EP disclosed