Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851662 | 0.95 | CHRM2 (0.49) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851618 | 0.95 | CHRM2 (0.49) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851603 | 0.93 | CHRM2 (0.57) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851630 | 0.89 | CHRM2 (0.50) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851695 | 0.88 | LMNA (0.58) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851551 | 0.88 | LMNA (0.58) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851717 | 0.88 | CHRM2 (0.50) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851693 | 0.88 | CHRM2 (0.50) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851637 | 0.88 | CHRM2 (0.50) | CHRM2LMNACHRM1USP2ALDH1A1 | |
| SCHEMBL9851613 | 0.88 | CHRM2 (0.52) | CHRM2LMNACHRM1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417631-A2 | Condensed diazepinones, process for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1991-03-20 | — | — | EP | disclosed |