Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851686 | 0.98 | CHRM1 (0.34) | PAOXTDP1CHRM1POLB | |
| SCHEMBL9851792 | 0.80 | CHRM1 (0.37) | PAOXCHRM1ACHE | |
| SCHEMBL9779511 | 0.79 | CHRM1 (0.34) | CHRM1 | |
| SCHEMBL9779592 | 0.78 | CHRM1 (0.35) | CHRM1 | |
| SCHEMBL9779487 | 0.74 | CHRM1 (0.59) | CHRM1 | |
| SCHEMBL9779728 | 0.69 | CHRM1 (0.44) | CHRM1 | |
| SCHEMBL11728208 | 0.69 | CHRM1 (0.53) | PAOXCHRM1 | |
| SCHEMBL22282294 | 0.68 | LMNA (0.40) | CHRM1POLBCYP4F2CYP4A11 | |
| SCHEMBL20373148 | 0.68 | LMNA (0.35) | TDP1 | |
| SCHEMBL9779570 | 0.67 | CHRM1 (0.37) | CHRM1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411616-A1 | 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents | WARNER-LAMBERT COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |