Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 4/20 | 0.49 |
| ▸ | PRKCA | P17252 | 5/20 | 0.40 |
| ▸ | TLR4 | O00206 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851697 | 1.00 | TK2 (0.49) | TK2PRKCATLR4SMN1; SMN2LMNA | |
| SCHEMBL9851708 | 0.93 | TK2 (0.56) | TK2PRKCA | |
| SCHEMBL9851692 | 0.93 | TK2 (0.56) | TK2PRKCA | |
| SCHEMBL9851814 | 0.93 | TK2 (0.56) | TK2PRKCA | |
| SCHEMBL9851871 | 0.93 | TK2 (0.47) | TK2PRKCATLR4LY96 | |
| SCHEMBL9851726 | 0.93 | TK2 (0.47) | TK2PRKCATLR4LY96 | |
| SCHEMBL9851791 | 0.92 | TK2 (0.42) | TK2SMN1; SMN2LMNA | |
| SCHEMBL9851850 | 0.92 | TK2 (0.42) | TK2SMN1; SMN2LMNA | |
| SCHEMBL9851753 | 0.87 | TK2 (0.46) | TK2SMN1; SMN2LMNA | |
| SCHEMBL9851891 | 0.87 | TK2 (0.46) | TK2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |