Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.37 |
| ▸ | ATG7 | O95352 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851850 | 1.00 | TK2 (0.42) | TK2LMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL9851891 | 0.93 | TK2 (0.46) | TK2LMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL9851753 | 0.93 | TK2 (0.46) | TK2LMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL9851734 | 0.93 | LMNA (0.45) | TK2LMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL9851712 | 0.93 | LMNA (0.45) | TK2LMNATHRBSMN1; SMN2HIF1A | |
| SCHEMBL9851694 | 0.92 | TK2 (0.49) | TK2LMNASMN1; SMN2 | |
| SCHEMBL9851697 | 0.92 | TK2 (0.49) | TK2LMNASMN1; SMN2 | |
| SCHEMBL9851715 | 0.92 | ATG7 (0.44) | ATG7GSK3ARPS6KA3MAPK14 | |
| SCHEMBL9851807 | 0.92 | ATG7 (0.44) | ATG7GSK3ARPS6KA3MAPK14 | |
| SCHEMBL9851692 | 0.87 | TK2 (0.56) | TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |