Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188371 | 0.93 | KDM4E (0.51) | ALDH1A1KDM4ELSSSMN1; SMN2HRH3 | |
| SCHEMBL1419119 | 0.88 | LTA4H (0.54) | ALDH1A1KDM4EMAPTLMNAHRH3 | |
| SCHEMBL919376 | 0.81 | KCNA3 (0.42) | ALDH1A1KDM4EKMT2ALMNALTA4H | |
| SCHEMBL5014110 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2LMNAMAOAHRH3 | |
| SCHEMBL9796880 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2LMNAMAOAHRH3 | |
| SCHEMBL6536652 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2LMNAMAOAHRH3 | |
| SCHEMBL533346 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2LMNAMAOAHRH3 | |
| SCHEMBL8420511 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2LMNAMAOAHRH3 | |
| SCHEMBL6050554 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2LMNAMAOAHRH3 | |
| SCHEMBL1712248 | 0.81 | KCNA3 (0.42) | ALDH1A1KDM4EKMT2ALMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410359-A1 | Substituted aminoalkoxy-benzene-derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |