Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490896 | 0.87 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL3490890 | 0.87 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL9851905 | 0.84 | CASR (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5ASAH2 | |
| SCHEMBL18660379 | 0.82 | CASR (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL18660381 | 0.82 | CASR (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8004701 | 0.82 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8004697 | 0.82 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL3487433 | 0.82 | PLA2G2A (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL3487439 | 0.82 | PLA2G2A (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL17445655 | 0.82 | CASR (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5ASAH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442612-A2 | Process of making (3H)-labeled PAF preparations | MERCK & CO. INC. (US) | 1991-08-21 | — | — | EP | disclosed |