SCHEMBL9851913

SCHEMBL9851913

Nc1ccc(Cc2ccc(C(F)(c3ccc(Cc4ccc(N)cc4)cc3)C(F)(F)C(F)(F)F)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.54
ALDH1A1 P00352 1/20 0.54
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MAOB P27338 4/20 0.42
KIF11 P52732 1/20 0.41
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
TAAR1 Q96RJ0 1/20 0.38
GFER P55789 1/20 0.38
LTA4H P09960 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
SRD5A2 P31213 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308187 0.88 KIF11 (0.50) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6366801 0.83 CYP3A4 (0.52) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6363970 0.81 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6362251 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6363243 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6362288 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6363090 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6363493 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6361851 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL6364026 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRTDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415447-A1 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP claimed
EP-0415447-A1 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed