Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633505 | 0.82 | CYP19A1 (0.50) | KDM4ECYP19A1CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL11354103 | 0.71 | CYP19A1 (0.69) | HTTKDM4EPOLBCYP19A1MEN1 | |
| Hydrochloric Acid SCHEMBL11358575 | 0.69 | CYP19A1 (0.67) | HTTKDM4EPOLBCYP19A1MEN1 | |
| SCHEMBL9851992 | 0.69 | SMN1; SMN2 (0.38) | L3MBTL1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL10564685 | 0.64 | CYP19A1 (0.44) | HTTKDM4EPOLBCYP19A1MEN1 | |
| SCHEMBL28956946 | 0.64 | IDO1 (0.56) | MEN1KMT2AALDH1A1MAPK1IDO1 | |
| SCHEMBL30927861 | 0.63 | MEN1 (0.62) | HTTKDM4EPOLBCYP19A1MEN1 | |
| SCHEMBL2347811 | 0.63 | CYP19A1 (0.48) | HTTKDM4EPOLBCYP19A1MEN1 | |
| SCHEMBL3674399 | 0.63 | CYP1A2 (0.63) | POLBMEN1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL1082679 | 0.63 | IDO1 (0.54) | L3MBTL1MEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422369-A2 | Substituted carbamoyltriazoles | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |