Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851974 | 0.82 | HTT (0.43) | CYP19A1SMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL6988243 | 0.72 | HSD17B10 (0.41) | CYP19A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11192201 | 0.71 | ALDH1A1 (0.45) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL22322 | 0.70 | NOTUM (0.41) | CYP19A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL25292589 | 0.68 | CYP19A1 (0.48) | CYP19A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19468086 | 0.68 | CA12 (0.45) | CYP19A1SMN1; SMN2LMNAMAPTHSP90AA1 | |
| SCHEMBL11293200 | 0.68 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11161275 | 0.67 | CYP19A1 (0.54) | CYP19A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2917482 | 0.67 | CYP19A1 (1.00) | CYP19A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5064961 | 0.67 | CYP3A4 (0.50) | CYP19A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210469-A1 | USE OF SUBSTITUTED THIO-1,2,4-TRIAZOLES FOR INCREASING STRESS TOLERANCE IN PLANTS | Bayer Cropscience AG (DE) | 2017-08-30 | — | — | EP | disclosed |
| EP-0487084-A2 | Image forming method and apparatus | CANON KABUSHIKI KAISHA (JP) | 1992-05-27 | — | — | EP | disclosed |