Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475682 | 0.79 | ALDH1A1 (0.51) | TSHRCYP2C19ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2219581 | 0.79 | TSHR (0.48) | TSHRALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL14008682 | 0.79 | TSHR (0.46) | TSHRCYP2C19ALDH1A1L3MBTL1MAPT | |
| SCHEMBL10845666 | 0.77 | TSHR (0.48) | TSHRALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL29191943 | 0.74 | TSHR (0.40) | TSHRALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL17281804 | 0.74 | TSHR (0.40) | TSHRALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL9512578 | 0.74 | TSHR (0.40) | TSHRALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL759137 | 0.72 | TSHR (0.52) | TSHRALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9125788 | 0.71 | TSHR (0.41) | TSHRALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL13732746 | 0.71 | TSHR (0.38) | TSHRALDH1A1L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729112-B2 | Antimicrobial haloalkyl heterocycle compounds | NOVABAY PHARMACEUTICALS, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-8729112-B2 | Antimicrobial haloalkyl heterocycle compounds | NOVABAY PHARMACEUTICALS, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| EP-0438311-A2 | Di- and tripeptide renin inhibitors | MERCK & CO. INC. (US) | 1991-07-24 | — | — | EP | disclosed |