Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852155 | 0.90 | CACNA1C (0.38) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852143 | 0.89 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL8865046 | 0.88 | CACNA1C (0.38) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852116 | 0.87 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852150 | 0.87 | CACNA1C (0.39) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852334 | 0.86 | CACNA1C (0.37) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL8865146 | 0.84 | CACNA1C (0.40) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852071 | 0.83 | CACNA1C (0.36) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL8865337 | 0.82 | KDM4E (0.33) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852342 | 0.82 | CACNA1C (0.36) | CACNA1CKDM4ELMNAESR1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |