Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852063 | 0.90 | LMNA (0.38) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL9852079 | 0.89 | KDM4E (0.36) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL9852089 | 0.88 | KDM4E (0.36) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL8864875 | 0.86 | KDM4E (0.38) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL9852072 | 0.84 | CACNA1C (0.34) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL9852332 | 0.83 | LMNA (0.38) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL9852407 | 0.82 | CACNA1C (0.35) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL8865296 | 0.79 | LMNA (0.35) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL9852143 | 0.79 | CACNA1C (0.34) | KDM4ELMNAESR1PTGS1PDE4A | |
| SCHEMBL9852188 | 0.79 | ELANE (0.37) | KDM4EESR1PTGS1PDE4ACACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672701-A | 4-substituted alkyl carbapenem antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-30 | — | — | US | disclosed |