Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.87 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.87 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.68 |
| ▸ | PDE2A | O00408 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571766 | 0.84 | PDE3B (1.00) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7333083 | 0.83 | PDE3B (1.00) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7334616 | 0.83 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7325332 | 0.83 | PDE3B (1.00) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7442793 | 0.82 | PDE3B (0.81) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7326865 | 0.82 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7334731 | 0.82 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10657958 | 0.81 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7335014 | 0.81 | PDE3B (0.81) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7327142 | 0.80 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426180-A2 | Imidazo[4,5-b] quinolinyloxyalkanoic acid amides with enhanced water solubility | Bristol-Myers Squibb Company (US) | 1991-05-08 | — | — | EP | claimed |