Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.59 |
| ▸ | CDC7 | O00311 | 6/20 | 0.59 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795516 | 0.83 | CDC7 (0.52) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL9795475 | 0.81 | MAPT (0.65) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL5641718 | 0.80 | CDC7 (0.68) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL9795379 | 0.80 | TRPM8 (0.48) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL6336462 | 0.80 | CDC7 (0.61) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL4163787 | 0.80 | CDC7 (0.79) | TRPM8CDC7DBF4MAPTALOX5 | |
| SCHEMBL15049067 | 0.79 | MAPT (0.50) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL15049187 | 0.79 | MEN1 (0.63) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL15049221 | 0.79 | MEN1 (0.63) | TRPM8CDC7DBF4MEN1MAPT | |
| SCHEMBL15049029 | 0.77 | CDC7 (0.67) | TRPM8CDC7DBF4MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422470-A2 | Thiazolcarboxylic acid amide derivatives | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |