SCHEMBL9852636

SCHEMBL9852636

COC(=O)c1ccccc1CS(=O)(=O)N(OC)C(=NS(=O)(=O)c1ccccc1C(=O)OC)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35
CYP1A2 P05177 1/20 0.34
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SLC40A1 Q9NP59 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9730664 0.74 KMT2A (0.37) MAPTTP53GLAKMT2AMEN1
Bensulfuron Methyl SCHEMBL29368260 0.74 GAA (0.51) MAPTTP53GLAKMT2ACYP1A2
Bensulfuron Methyl SCHEMBL6382944 0.74 GAA (0.51) MAPTTP53GLAKMT2ACYP1A2
Bensulfuron Methyl SCHEMBL27491070 0.74 GAA (0.51) MAPTTP53GLAKMT2ACYP1A2
Bensulfuron Methyl SCHEMBL55028 0.74 GAA (0.51) MAPTTP53GLAKMT2ACYP1A2
SCHEMBL8159483 0.73 MAPT (0.44) MAPTTP53GLAKMT2AMEN1
SCHEMBL1765911 0.73 MAPT (0.47) MAPTTP53GLAKMT2AMEN1
SCHEMBL10524876 0.73 MAPT (0.48) MAPTTP53GLAKMT2ACYP1A2
Bensulfuron Methyl SCHEMBL15524972 0.73 GAA (0.50) MAPTTP53GLAKMT2ACYP1A2
SCHEMBL9835967 0.73 MAPT (0.46) MAPTTP53GLAKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0431270-A1 Substituted sulfonylamidinohydrazones BAYER AG (DE) 1991-06-12 EP disclosed