SCHEMBL1765911

SCHEMBL1765911

COC(=O)c1ccccc1CS(=O)(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.75

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TSHR P16473 2/20 0.47
RORC P51449 1/20 0.45
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.41
HIF1A Q16665 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bensulfuron Methyl SCHEMBL6382944 0.86 GAA (0.51) MAPTTP53GLASMN1; SMN2ALDH1A1
Bensulfuron Methyl SCHEMBL27491070 0.86 GAA (0.51) MAPTTP53GLASMN1; SMN2ALDH1A1
Bensulfuron Methyl SCHEMBL29368260 0.86 GAA (0.51) MAPTTP53GLASMN1; SMN2ALDH1A1
Bensulfuron Methyl SCHEMBL55028 0.86 GAA (0.51) MAPTTP53GLASMN1; SMN2ALDH1A1
SCHEMBL10524876 0.85 MAPT (0.48) MAPTTP53GLASMN1; SMN2TSHR
Bensulfuron Methyl SCHEMBL15524972 0.85 GAA (0.50) MAPTTP53GLASMN1; SMN2ALDH1A1
SCHEMBL8159477 0.85 ALDH1A1 (0.43) MAPTTP53GLASMN1; SMN2TSHR
SCHEMBL10394921 0.84 MAPT (0.51) MAPTTP53GLASMN1; SMN2TSHR
SCHEMBL9461802 0.83 ALDH1A1 (0.43) MAPTTP53GLASMN1; SMN2TSHR
SCHEMBL9835952 0.82 MAPT (0.46) MAPTTP53GLASMN1; SMN2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050238693-A1 Process for the preparation and activation of susbstances and a means of producing same CHEMSTOP PTY LTD. (AU) 2005-10-27 US claimed
CN-1655815-A Method for preparing and activating substance and apparatus for preparing the same CHEMSTOP PTY LTD (AU) 2005-08-17 CN claimed
EP-0529975-B1 Slow release compositions DU PONT (US) 1995-11-22 EP claimed
US-5229356-A SLOW RELEASE COMPOSITIONS COMPRISING HETEROCYCLIC SULFONYLUREA HERBICIDES, PARAFFIN WAX, HYDROCARBON POLYMERS, AND PARTICULATE FILLERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-20 US claimed
CN-1069853-A Slow release compositions DU PONT (US) 1993-03-17 CN claimed
EP-0529975-A1 Slow release compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-03 EP claimed
US-20240373844-A1 PYROGLUTAMIC ACID AS AN HERBICIDE SAFENER AND METHODS OF USE THEREOF PNC BANK, NATIONAL ASSOCIATION 2024-11-14 US disclosed
EP-4391807-A1 PYROGLUTAMIC ACID AS AN HERBICIDE SAFENER AND METHODS OF USE THEREOF Verdesian Life Sciences U.S., LLC (US) 2024-07-03 EP disclosed
WO-2023043648-A1 PYROGLUTAMIC ACID AS AN HERBICIDE SAFENER AND METHODS OF USE THEREOF VERDESIAN LIFE SCIENCES U.S., LLC (US) 2023-03-23 WO disclosed
CN-115088711-A Spreading agent for water-surface floating type pesticide composition and pesticide composition containing same 竹本油脂株式会社 2022-09-23 CN disclosed
CN-113693061-B Spreading agent for water-surface floating type pesticide composition and pesticide composition containing same 竹本油脂株式会社 2022-07-08 CN disclosed
CN-113693061-A Spreading agent for water-surface floating type pesticide composition and pesticide composition containing same 竹本油脂株式会社 2021-11-26 CN disclosed
CN-108697084-B Synergistic herbicidal compositions and methods for controlling undesired plant growth 江苏龙灯化学有限公司 2021-06-25 CN disclosed
US-4973713-A HEAVY METAL CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-27 US disclosed
EP-0377642-A1 HERBICIDES FOR WEED CONTROL IN RICE. DU PONT (US) 1990-07-18 EP disclosed
US-4913722-A HERBICIDES ICI AMERICAS INC. (US) 1990-04-03 US disclosed
EP-0360441-A1 Water-soluble or water-dispersible pesticide granules E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-28 EP disclosed
WO-1990002486-A1 WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-22 WO disclosed
EP-0318253-A1 Iminophenylthiazolidines, process of preparation, and method of use ICI AMERICAS INC. (US) 1989-05-31 EP disclosed
WO-1989001289-A1 HERBICIDES FOR WEED CONTROL IN RICE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240373844-A1 PYROGLUTAMIC ACID AS AN HERBICIDE SAFENER AND METHODS OF USE THEREOF PGAM1, FPGS, GLUL MAPT 3038/4885TP53 852/4885GLA 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.