Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trovafloxacin10 SCHEMBL9178909 | 1.00 | DPP4 (0.59) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9181756 | 0.86 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9182408 | 0.83 | DPP4 (0.51) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9184745 | 0.83 | EPHA2 (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9066532 | 0.82 | DPP4 (0.61) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL27484168 | 0.82 | DPP4 (0.61) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9066828 | 0.82 | DPP4 (0.61) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL28745952 | 0.82 | DPP4 (0.63) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9185272 | 0.82 | KDM4E (0.60) | LMNAKDM4EHSD17B10KCNH2TOP2A | |
| Hydrochloric Acid SCHEMBL27521147 | 0.82 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413455-A2 | Azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1991-02-20 | — | — | EP | disclosed |