Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27554040 | 0.99 | DPP4 (0.60) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL28745952 | 0.90 | DPP4 (0.63) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL27486246 | 0.89 | DPP4 (0.55) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL27521147 | 0.89 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL8775460 | 0.88 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL27486245 | 0.84 | DPP4 (0.57) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9572096 | 0.83 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| Trovafloxacin9 SCHEMBL9186378 | 0.83 | DPP4 (0.66) | DPP4CHRM2DRD1LMNAKDM4E | |
| Trovafloxacin9 SCHEMBL9186361 | 0.83 | DPP4 (0.66) | DPP4CHRM2DRD1LMNAKDM4E | |
| Trovafloxacin10 SCHEMBL9852769 | 0.82 | DPP4 (0.59) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184221-C | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1184221-C | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1400209-A | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2003-03-05 | — | — | CN | disclosed |