Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658077 | 0.82 | KDM4E (0.35) | MAPT | |
| SCHEMBL7660795 | 0.81 | CYP2A6 (0.36) | CYP2A6NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8186459 | 0.81 | KMT2A (0.36) | CYP2A6MAPT | |
| SCHEMBL5544270 | 0.79 | CYP2A6 (0.33) | CYP2A6L3MBTL1 | |
| SCHEMBL8192441 | 0.77 | ADH1B (0.44) | CYP2A6NPC1SMN1; SMN2 | |
| SCHEMBL5544459 | 0.77 | GAA (0.33) | CYP2A6L3MBTL1 | |
| SCHEMBL5536213 | 0.76 | GAA (0.32) | CYP2A6L3MBTL1 | |
| SCHEMBL5537190 | 0.75 | CYP2A6 (0.34) | CYP2A6NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9852782 | 0.75 | — | — | |
| SCHEMBL5540452 | 0.74 | GAA (0.31) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |