Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167294 | 0.83 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL10399110 | 0.83 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL832849 | 0.80 | EPHX1 (0.46) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL6008512 | 0.79 | UGT2B7 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL11754330 | 0.75 | ALDH1A1 (0.54) | CYP2D6PPARGPPARA | |
| SCHEMBL28201253 | 0.75 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL28313381 | 0.75 | TACR1 (0.42) | SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL27523720 | 0.74 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL4017223 | 0.74 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL28456177 | 0.72 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |