Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.45 |
| ▸ | ADH1C | P00326 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 1/20 | 0.45 |
| ▸ | ADH7 | P40394 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5965957 | 0.84 | TAAR1 (0.47) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7515008 | 0.81 | KCNA5 (0.39) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7520967 | 0.81 | KCNA5 (0.39) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL20856895 | 0.81 | TAAR1 (0.44) | ALDH1A1CYP2C19HIF1AKMT2AMEN1 | |
| SCHEMBL29257171 | 0.79 | ADH1B (0.48) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL23353938 | 0.76 | MEN1 (0.49) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL10145455 | 0.74 | KCNN4 (0.46) | ALDH1A1CYP2C19HIF1AKMT2AMEN1 | |
| SCHEMBL9340362 | 0.73 | CYP2C19 (0.39) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL4454569 | 0.73 | TAAR1 (0.44) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL9340359 | 0.72 | CYP2C19 (0.42) | ALDH1A1CYP2C19HIF1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |