Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911380 | 0.82 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL31086285 | 0.78 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL2074399 | 0.76 | KCNN4 (0.48) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL14705861 | 0.75 | TAAR1 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL1455028 | 0.75 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL1455851 | 0.75 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL1455027 | 0.75 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL28059566 | 0.74 | ALDH1A1 (0.38) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL28687787 | 0.73 | KCNN4 (0.44) | KCNN4ALDH1A1KMT2AMAPTADH1B | |
| SCHEMBL11622569 | 0.72 | ALDH1A1 (0.35) | HDAC3HDAC1HDAC2HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103583-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-07-09 | — | — | WO | disclosed |
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |