Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.59 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.59 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852932 | 0.88 | — | — | |
| SCHEMBL9852940 | 0.82 | — | — | |
| SCHEMBL9852953 | 0.82 | — | — | |
| SCHEMBL9852997 | 0.82 | — | — | |
| SCHEMBL9852869 | 0.81 | CACNA2D1 (0.61) | CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL9574962 | 0.80 | — | — | |
| SCHEMBL28695334 | 0.78 | HSD11B1 (0.64) | — | |
| SCHEMBL9852946 | 0.77 | — | — | |
| SCHEMBL26330969 | 0.77 | CACNA2D1 (0.81) | CACNA1HCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL9853114 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | claimed |
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |