Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549012 | 0.72 | HDAC3 (0.45) | KCNN4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL27948873 | 0.72 | KCNN4 (0.61) | KCNN4LMNAHTTL3MBTL1NR3C2 | |
| SCHEMBL3114470 | 0.72 | HDAC3 (0.45) | KCNN4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28262161 | 0.72 | KCNN4 (0.45) | KCNN4NR3C2TAAR1KIF11 | |
| SCHEMBL28397743 | 0.72 | CYP2C19 (0.42) | KCNN4LMNAHTTL3MBTL1HDAC1 | |
| SCHEMBL9853013 | 0.72 | KCNN4 (0.41) | KCNN4LMNAHTTL3MBTL1HDAC1 | |
| SCHEMBL2074396 | 0.72 | KCNN4 (0.48) | KCNN4LMNAHTTL3MBTL1HDAC1 | |
| SCHEMBL28778295 | 0.71 | CYP2C19 (0.46) | KCNN4LMNAHTTL3MBTL1HDAC1 | |
| SCHEMBL9318575 | 0.71 | KCNN4 (0.44) | KCNN4LMNAALDH1A1TAAR1CYP3A4 | |
| SCHEMBL3665471 | 0.69 | HDAC3 (0.47) | KCNN4LMNAHTTL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |