SCHEMBL9853013

SCHEMBL9853013

CCC(NC=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.41
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH7 P40394 1/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TAAR1 Q96RJ0 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NR3C2 P08235 1/20 0.35
HIF1A Q16665 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HDAC1 Q13547 2/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318004 0.79 KCNN4 (0.41) KCNN4ADH1BADH1CADH1AADH7
SCHEMBL14705861 0.78 TAAR1 (0.41) KCNN4ADH1BADH1CADH1AADH7
SCHEMBL8048285 0.74 ALDH1A1 (0.39) KCNN4CYP2C19ALDH1A1MEN1KMT2A
SCHEMBL8038268 0.74 ALDH1A1 (0.39) KCNN4CYP2C19ALDH1A1MEN1KMT2A
SCHEMBL8048287 0.74 ALDH1A1 (0.39) KCNN4CYP2C19ALDH1A1MEN1KMT2A
SCHEMBL1911380 0.72 HDAC3 (0.41) KCNN4ADH1BADH1CADH1AADH7
SCHEMBL28687787 0.72 KCNN4 (0.44) KCNN4ADH1BADH1CADH1AADH7
SCHEMBL27948873 0.72 KCNN4 (0.61) KCNN4CYP3A4TAAR1NR3C2LMNA
SCHEMBL9852913 0.72 HDAC3 (0.41) KCNN4ADH1BADH1CADH1AADH7
SCHEMBL28262161 0.72 KCNN4 (0.45) KCNN4TAAR1KMT2ANR3C2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0441226-A1 (cyanomethyl)pyridines useful as PAF antagonists J. URIACH & CIA. S.A. (ES) 1991-08-14 EP disclosed