Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 17/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 15/20 | 0.41 |
| ▸ | MEN1 | O00255 | 14/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991967 | 0.78 | GAA (0.38) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL11274257 | 0.73 | GAA (0.40) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL244451 | 0.69 | — | — | |
| SCHEMBL7204796 | 0.69 | CLCN2 (0.38) | GAAKMT2AMAPTHTTALDH1A1 | |
| SCHEMBL27672844 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL22712590 | 0.67 | — | — | |
| Iodide SCHEMBL22712589 | 0.67 | — | — | |
| Bromide SCHEMBL22712592 | 0.67 | — | — | |
| SCHEMBL9399546 | 0.67 | GAA (0.41) | GAAKMT2AMAPTHSD17B10HPGD | |
| Propanol SCHEMBL27976426 | 0.67 | GAA (0.41) | GAAKMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413293-A2 | 1-(Benzo[b]thienyl)-2-(thienyl) ethenes and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4904674-A | FREE OF AGGLOMERATION OF FIBRILLATION | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-02-27 | — | — | US | disclosed |