SCHEMBL9853227

SCHEMBL9853227

C1CCCNCCC1.CO[SiH](C)OC

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
CXCR4 P61073 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL8583486 0.82
Azepane SCHEMBL554686 0.80 ALDH1A1 (0.53) ALDH1A1CXCR4SMN1; SMN2
Azepane SCHEMBL28300473 0.78 ALDH1A1 (0.69) ALDH1A1CXCR4SMN1; SMN2
Piperidine SCHEMBL28503554 0.78 ALDH1A1 (0.50) ALDH1A1CXCR4SMN1; SMN2
Cyclopropane SCHEMBL28928234 0.76
Cyclopropane SCHEMBL734540 0.73 ALDH1A1 (0.41) ALDH1A1CXCR4SMN1; SMN2
Piperidine SCHEMBL10008663 0.71 ALDH1A1 (0.82) ALDH1A1CXCR4SMN1; SMN2
Piperidine SCHEMBL11714957 0.71
SCHEMBL11508384 0.71 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2
Piperidine SCHEMBL11283826 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0410443-A1 Organosilane compounds MONTELL NORTH AMERICA INC. (US) 1991-01-30 EP disclosed