Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.50 |
| ▸ | GBA1 | P04062 | 5/20 | 0.50 |
| ▸ | UGCG | Q16739 | 4/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815008 | 0.90 | GBA2 (0.60) | GBA2GBA1UGCGCNR2CNR1 | |
| SCHEMBL9853333 | 0.86 | GBA2 (0.45) | GBA2GBA1UGCGMEN1KMT2A | |
| SCHEMBL10436525 | 0.86 | GBA1 (0.45) | GBA2GBA1UGCGCNR2CNR1 | |
| SCHEMBL1007564 | 0.82 | CNR2 (0.47) | GBA2GBA1UGCGCNR2CNR1 | |
| SCHEMBL27523973 | 0.80 | MEN1 (0.50) | GBA2GBA1UGCGCNR2MEN1 | |
| SCHEMBL9853348 | 0.80 | GBA1 (0.35) | GBA2GBA1UGCGCNR2CNR1 | |
| SCHEMBL9853338 | 0.79 | HTR1B (0.40) | GBA2GBA1UGCGMEN1KMT2A | |
| SCHEMBL4239401 | 0.75 | GBA2 (0.54) | GBA2GBA1UGCGMEN1KMT2A | |
| SCHEMBL13951801 | 0.75 | GBA1 (0.54) | GBA2GBA1UGCGCNR2CNR1 | |
| SCHEMBL4236889 | 0.75 | GBA2 (0.54) | GBA2GBA1UGCGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417535-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-20 | — | — | EP | disclosed |