Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | UGCG | Q16739 | 2/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816053 | 0.89 | GBA1 (0.46) | HTR1BGBA1UGCGGBA2CYP1A2 | |
| SCHEMBL9853333 | 0.88 | GBA2 (0.45) | HTR1BGBA1UGCGGBA2CYP1A2 | |
| SCHEMBL29641182 | 0.80 | HTR1B (0.53) | HTR1BCYP1A2HPGDMEN1KMT2A | |
| SCHEMBL4614172 | 0.80 | HTR1B (0.53) | HTR1BCYP1A2HPGDMEN1KMT2A | |
| SCHEMBL10436525 | 0.79 | GBA1 (0.45) | HTR1BGBA1UGCGGBA2KDM4E | |
| SCHEMBL9853277 | 0.79 | GBA2 (0.50) | HTR1BGBA1UGCGGBA2CYP1A2 | |
| SCHEMBL9815003 | 0.77 | GBA2 (0.54) | HTR1BGBA1UGCGGBA2CYP1A2 | |
| SCHEMBL4229167 | 0.77 | GBA2 (0.54) | HTR1BGBA1UGCGGBA2CYP1A2 | |
| SCHEMBL4236889 | 0.77 | GBA2 (0.54) | HTR1BGBA1UGCGGBA2CYP1A2 | |
| SCHEMBL20683224 | 0.77 | ALDH1A1 (0.43) | HTR1BCYP1A2ALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417535-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-20 | — | — | EP | disclosed |