Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853525 | 0.81 | SMN1; SMN2 (0.46) | GAANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9853497 | 0.81 | SMN1; SMN2 (0.46) | GAANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9853577 | 0.81 | SMN1; SMN2 (0.46) | GAANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL1569037 | 0.79 | GAA (0.58) | MAPK14L3MBTL1GAAKMT2AMAPT | |
| SCHEMBL31366601 | 0.79 | GAA (0.58) | MAPK14L3MBTL1GAAKMT2AMAPT | |
| SCHEMBL11320349 | 0.70 | AKR1C3 (0.53) | L3MBTL1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6004442 | 0.70 | MAPT (0.46) | MAPK14L3MBTL1GAAKMT2AMAPT | |
| SCHEMBL11320848 | 0.69 | NR4A1 (0.56) | MAPK14NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11322571 | 0.69 | KMT2A (0.72) | GAANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10931534 | 0.68 | MAPT (0.53) | MAPK14GAAKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | disclosed |