SCHEMBL9853620

SCHEMBL9853620

O=C/C=C/CCCCCC(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
ACLY P53396 1/20 0.33
FAAH O00519 3/20 0.30
CES1 P23141 2/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8666737 1.00 ALDH1A1 (0.39) ALDH1A1TSHRACLYFAAHCES1
SCHEMBL8666739 1.00 ALDH1A1 (0.39) ALDH1A1TSHRACLYFAAHCES1
SCHEMBL8665542 0.83 ALDH1A1 (0.42) ALDH1A1TSHRACLYFAAHCES1
SCHEMBL8665544 0.83 ALDH1A1 (0.42) ALDH1A1TSHRACLYFAAHCES1
SCHEMBL848156 0.79 TSHR (0.42) TSHRFAAH
SCHEMBL19554091 0.79 TSHR (0.42) TSHRFAAH
SCHEMBL10546638 0.79 TSHR (0.42) TSHRFAAH
SCHEMBL31607965 0.77 TSHR (0.48) ALDH1A1TSHRACLYFAAHTRPA1
SCHEMBL1782360 0.74 ALDH1A1 (0.50) ALDH1A1TSHRACLYFAAHTRPA1
SCHEMBL1782363 0.74 ALDH1A1 (0.50) ALDH1A1TSHRACLYFAAHTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0419411-A2 Additional alkanophenones CIBA-GEIGY AG (CH) 1991-03-27 EP disclosed