Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.76 |
| ▸ | HTR1A | P08908 | 4/20 | 0.76 |
| ▸ | DRD2 | P14416 | 4/20 | 0.76 |
| ▸ | DRD4 | P21917 | 4/20 | 0.76 |
| ▸ | DRD5 | P21918 | 4/20 | 0.76 |
| ▸ | HTR1D | P28221 | 4/20 | 0.76 |
| ▸ | HTR1E | P28566 | 4/20 | 0.76 |
| ▸ | HTR7 | P34969 | 4/20 | 0.76 |
| ▸ | HRH1 | P35367 | 4/20 | 0.76 |
| ▸ | DRD3 | P35462 | 4/20 | 0.76 |
| ▸ | HTR2B | P41595 | 4/20 | 0.76 |
| ▸ | HTR5A | P47898 | 4/20 | 0.76 |
| ▸ | HTR6 | P50406 | 4/20 | 0.76 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.76 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.76 |
| ▸ | HTR2C | P28335 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853852 | 1.00 | HTR2A (0.76) | HTR2AHTR1ADRD2DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL9853861 | 0.99 | HTR2A (0.75) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL26265036 | 0.92 | HTR2A (0.79) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL30886877 | 0.91 | HTR2A (0.80) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL2469887 | 0.91 | HTR2A (0.80) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL29556822 | 0.89 | HTR2A (0.80) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL29556873 | 0.87 | HTR2A (0.75) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL20970957 | 0.87 | HTR2A (0.75) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL25545441 | 0.87 | HTR2A (0.75) | HTR2AHTR1ADRD2DRD4DRD5 | |
| SCHEMBL28377126 | 0.87 | HTR2A (0.77) | HTR2AHTR1ADRD2DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411494-A2 | Ergoline derivatives having dopaminergic activity | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1991-02-06 | — | — | EP | disclosed |