Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL9854098 | 0.87 | PTAFR (0.58) | PTAFRALDH1A1TBXAS1 | |
| SCHEMBL9853936 | 0.86 | PTAFR (0.61) | PTAFRTBXAS1 | |
| SCHEMBL9853918 | 0.86 | PTAFR (0.59) | PTAFRTBXAS1 | |
| SCHEMBL9854014 | 0.86 | PTAFR (0.59) | PTAFRTBXAS1 | |
| SCHEMBL9854059 | 0.85 | PTAFR (0.58) | PTAFRPOLBLMNAKDM4ETDP1 | |
| SCHEMBL9854048 | 0.85 | PTAFR (0.58) | PTAFRPOLBRAB9ALMNAMAPT | |
| SCHEMBL9853917 | 0.85 | PTAFR (0.58) | PTAFRTBXAS1 | |
| SCHEMBL9853995 | 0.85 | PTAFR (0.58) | PTAFRTBXAS1 | |
| SCHEMBL9854042 | 0.85 | PTAFR (0.58) | PTAFRTBXAS1GAA | |
| SCHEMBL9853955 | 0.85 | PTAFR (0.58) | PTAFRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |