Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | PTAFR | P25105 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854003 | 0.97 | PTAFR (0.51) | TBXAS1PTAFRMAPK1TSHRALDH1A1 | |
| SCHEMBL9853908 | 0.91 | PTAFR (0.53) | TBXAS1PTAFRMAPK1TSHRALDH1A1 | |
| SCHEMBL9854100 | 0.90 | PTAFR (0.52) | TBXAS1PTAFRMAPK1TSHRNR1H4 | |
| SCHEMBL9853973 | 0.90 | PTAFR (0.49) | TBXAS1PTAFRMAPK1TSHRALDH1A1 | |
| SCHEMBL9854116 | 0.89 | PTAFR (0.53) | TBXAS1PTAFRMAPK1TSHRNR1H4 | |
| SCHEMBL9854056 | 0.89 | PTAFR (0.50) | TBXAS1PTAFRMAPK1TSHRKMT2A | |
| SCHEMBL9854123 | 0.88 | PTAFR (0.53) | TBXAS1PTAFRMAPK1TSHR | |
| SCHEMBL9853944 | 0.88 | PTAFR (0.54) | TBXAS1PTAFRMAPK1TSHRNR1H4 | |
| SCHEMBL9853960 | 0.87 | PTAFR (0.56) | TBXAS1PTAFRTSHRALDH1A1KMT2A | |
| SCHEMBL9853933 | 0.86 | PTAFR (0.51) | TBXAS1PTAFRMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |