Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MYOF | Q9NZM1 | 1/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854116 | 0.99 | PTAFR (0.53) | PTAFRTBXAS1TSHRMAPK1MYOF | |
| SCHEMBL9854123 | 0.97 | PTAFR (0.53) | PTAFRTBXAS1TSHRMAPK1MYOF | |
| SCHEMBL9853944 | 0.95 | PTAFR (0.54) | PTAFRTBXAS1TSHRMAPK1GPR132 | |
| SCHEMBL9853969 | 0.90 | TBXAS1 (0.51) | PTAFRTBXAS1TSHRMAPK1NR1H4 | |
| SCHEMBL9854060 | 0.90 | PTAFR (0.55) | PTAFRTSHRGPR132 | |
| SCHEMBL9854003 | 0.88 | PTAFR (0.51) | PTAFRTBXAS1TSHRMAPK1NR1H4 | |
| SCHEMBL9853973 | 0.86 | PTAFR (0.49) | PTAFRTBXAS1TSHRMAPK1NR1H4 | |
| SCHEMBL9853908 | 0.86 | PTAFR (0.53) | PTAFRTBXAS1TSHRMAPK1 | |
| SCHEMBL9854002 | 0.86 | PTAFR (0.59) | PTAFRTBXAS1 | |
| SCHEMBL9853951 | 0.86 | PTAFR (0.59) | PTAFRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |