SCHEMBL9854004

SCHEMBL9854004

O=C(O)c1cccc(C(=O)c2ccc(Cl)cc2)c1

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 7/20 0.70
ATM Q13315 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
NR4A1 P22736 1/20 0.55
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
MAPK1 P28482 1/20 0.53
RXRA P19793 1/20 0.53
RXRB P28702 1/20 0.53
MRGPRX4 Q96LA9 1/20 0.51
NR4A2 P43354 1/20 0.51
KDM4E B2RXH2 1/20 0.50
CNR1 P21554 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809735 0.92 ATM (0.67) SRD5A2ATMTDP1L3MBTL1ALOX15
SCHEMBL110317 0.88 SRD5A2 (0.74) SRD5A2ATMTDP1L3MBTL1TSHR
SCHEMBL9727858 0.86 SRD5A2 (0.78) SRD5A2ATMTDP1L3MBTL1TSHR
SCHEMBL30320253 0.86 ATM (0.86) SRD5A2ATMTDP1L3MBTL1TSHR
SCHEMBL141056 0.86 ATM (0.86) SRD5A2ATMTDP1L3MBTL1TSHR
SCHEMBL2405473 0.86 SRD5A2 (0.77) SRD5A2ATMTDP1L3MBTL1TSHR
SCHEMBL766131 0.85 ATM (0.76) SRD5A2ATMTDP1L3MBTL1TSHR
SCHEMBL11453670 0.85 ATM (0.57) SRD5A2ATMTDP1L3MBTL1TSHR
SCHEMBL8437706 0.85 SRD5A2 (0.64) SRD5A2ATMTDP1L3MBTL1ALOX15
SCHEMBL3177794 0.84 PARP1 (0.59) SRD5A2ATMTDP1L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11215935-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-01-04 US disclosed
US-11169455-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2021-11-09 US disclosed
US-20200341393-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-20200341392-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-10754266-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2020-08-25 US disclosed
US-20200096884-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO.,LTD. (JP) 2020-03-26 US disclosed
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed
US-4192890-A Novel benzoylphenylacetic acid esters ROUSSEL UCLAF (FR) 1980-03-11 US disclosed