SCHEMBL809735

SCHEMBL809735

O=C(c1ccc(Cl)cc1)c1cccc(C(=O)c2ccc(Cl)cc2)c1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
SRD5A2 P31213 1/20 0.61
MAPK1 P28482 1/20 0.61
CES2 O00748 2/20 0.56
CES1 P23141 2/20 0.56
HPGD P15428 1/20 0.53
NR4A1 P22736 1/20 0.52
CNR1 P21554 2/20 0.52
CNR2 P34972 1/20 0.52
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
PBRM1 Q86U86 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HSD17B1 P14061 2/20 0.49
HSD17B2 P37059 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854004 0.92 SRD5A2 (0.70) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL11453670 0.92 ATM (0.57) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL3177794 0.91 PARP1 (0.59) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL12274592 0.88 SRD5A2 (0.70) SRD5A2MAPK1CES2CES1HPGD
SCHEMBL9468917 0.88 MAPK1 (0.64) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL3445668 0.86 PARP1 (0.63) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL7280496 0.86 SRD5A2 (0.52) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL1128726 0.86 CES2 (0.57) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL7271928 0.86 CNR2 (0.60) ATMTDP1L3MBTL1SRD5A2MAPK1
SCHEMBL9353635 0.86 FLT1 (0.55) ATMTDP1L3MBTL1SRD5A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652421-A Application of composite catalyst in preparation of amorphous polyaryletherketone, amorphous polyaryletherketone and preparation method and application thereof 吉林大学 2024-09-17 CN claimed
CN-113769592-B Quaternized modified polyarylether membrane material and preparation method and application thereof 吉林大学 2022-06-24 CN claimed
CN-112546883-B Polyelectrolyte, preparation and application thereof, polyelectrolyte ultrafiltration membrane, preparation and application thereof 吉林大学 2022-02-15 CN claimed
US-7481959-B2 Method for controlling haze in an article comprising a polymer composition SABIC INNOVATIVE PLASTICS IP B.V. (US) 2009-01-27 US claimed
US-20060066004-A1 Method for controlling haze in an article comprising a polymer composition GENERAL ELECTRIC COMPANY 2006-03-30 US claimed
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
US-12297326-B2 Copolymers, their preparation and use VICTREX MANUFACTURING LIMITED (GB) 2025-05-13 US disclosed
CN-116157471-B Copolymers, their preparation and use 威格斯制造有限公司 2024-11-22 CN disclosed
CN-118652421-A Application of composite catalyst in preparation of amorphous polyaryletherketone, amorphous polyaryletherketone and preparation method and application thereof 吉林大学 2024-09-17 CN disclosed
US-12024588-B2 Copolymers and process for their manufacture VICTREX MANUFACTURING LIMITED (GB) 2024-07-02 US disclosed
CN-111902456-B Copolymer and method for producing same 威格斯制造有限公司 2024-01-05 CN disclosed
EP-3774991-B1 COPOLYMERS AND PROCESS FOR THEIR MANUFACTURE VICTREX MFG LTD (GB) 2023-12-27 EP disclosed
EP-0389902-A1 Process for producing aromatic polyetherketones BAYER AG (DE) 1990-10-03 EP disclosed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US disclosed
EP-0323076-A2 Polyaryletherketones VICTREX MANUFACTURING LIMITED (GB) 1989-07-05 EP disclosed
US-4814224-A FIBER-REINFORCED MOLDING MATERIALS PHILLIPS PETROLEUM COMPANY (US) 1989-03-21 US disclosed
EP-0274754-A2 Poly (arylene sulfide ketone) composites PHILLIPS PETROLEUM COMPANY (US) 1988-07-20 EP disclosed
US-4590104-A Production of fiber-reinforced materials BASF AKTIENGESELLSCHAFT (DE) 1986-05-20 US disclosed