Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853988 | 0.89 | PTAFR (0.55) | PTAFRPOLBTBXAS1 | |
| SCHEMBL9854130 | 0.87 | PTAFR (0.51) | PTAFRPOLBTSHRSMN1; SMN2TBXAS1 | |
| SCHEMBL9853960 | 0.86 | PTAFR (0.56) | PTAFRPOLBTSHRSMN1; SMN2TBXAS1 | |
| SCHEMBL9854005 | 0.86 | PTAFR (0.53) | PTAFRPOLBTSHRSMN1; SMN2TBXAS1 | |
| Water SCHEMBL9853929 | 0.85 | LMNA (0.52) | PTAFRPOLBTSHRSMN1; SMN2TBXAS1 | |
| SCHEMBL9853980 | 0.85 | PTAFR (0.57) | PTAFRTBXAS1 | |
| Water SCHEMBL9854050 | 0.84 | POLB (0.52) | PTAFRPOLBSMN1; SMN2TBXAS1 | |
| Water SCHEMBL9854045 | 0.84 | POLB (0.52) | PTAFRPOLBSMN1; SMN2TBXAS1 | |
| SCHEMBL10688871 | 0.83 | PTAFR (0.59) | PTAFRTBXAS1 | |
| SCHEMBL9854118 | 0.82 | PTAFR (0.60) | PTAFRPOLBTSHRSMN1; SMN2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |