SCHEMBL9854150

SCHEMBL9854150

CC(C)(C)C(O)C=C(c1ccc(Cl)cc1Cl)n1cncn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.47
ALDH1A1 P00352 5/20 0.46
MAPT P10636 3/20 0.46
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
GABRA1 P14867 1/20 0.46
TSHR P16473 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
LMNA P02545 4/20 0.45
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSP90AA1 P07900 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PKM P14618 2/20 0.43
MAPK1 P28482 1/20 0.43
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10923584 1.00 CYP19A1 (0.47) CYP19A1ALDH1A1MAPTHPGDCYP1A2
SCHEMBL9854146 1.00 CYP19A1 (0.47) CYP19A1ALDH1A1MAPTHPGDCYP1A2
SCHEMBL9580993 0.83 ALDH1A1 (0.56) CYP19A1ALDH1A1MAPTHPGDCYP3A4
SCHEMBL9580995 0.83 ALDH1A1 (0.56) CYP19A1ALDH1A1MAPTHPGDCYP3A4
SCHEMBL10503638 0.79 CYP19A1 (0.52) CYP19A1ALDH1A1MAPTHPGDCYP1A2
SCHEMBL10503633 0.79 CYP19A1 (0.52) CYP19A1ALDH1A1MAPTHPGDCYP1A2
SCHEMBL11380534 0.76 ALDH1A1 (0.50) CYP19A1ALDH1A1MAPTHPGDCYP1A2
SCHEMBL10869121 0.75 ALDH1A1 (0.45) CYP19A1ALDH1A1MAPTHPGDCYP1A2
SCHEMBL10824908 0.75 ALDH1A1 (0.50) CYP19A1ALDH1A1MAPTHPGDCYP1A2
Diniconazole SCHEMBL41498 0.74 ALDH1A1 (0.55) CYP19A1ALDH1A1MAPTHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427168-A1 Optical isomer of triazolylpentenols, and their production and use as fungicide, herbicide and/or plant growth regulant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-15 EP disclosed
US-4435203-A 1-(4-CHLORO- OR 2,4-DICHLORO-PHENYL)-2-(1,2,4-TRIAZOL-1-YL)-4,4-DIMETHYLPENT-1-EN-3-OL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-03-06 US disclosed