Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 7/20 | 0.40 |
| ▸ | CES1 | P23141 | 5/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332419 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL9639022 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL8950093 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL1260244 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL1260468 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL1259905 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL1038699 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL9727189 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL11380532 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH | |
| SCHEMBL9356367 | 0.84 | CA2 (0.59) | CA2MAPTGRIK1GRIK2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282391-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1991-08-21 | — | — | EP | disclosed |
| EP-0282391-A1 | Process for the preparation of trifluoromethyl compounds | RHONE-POULENC CHIMIE (FR) | 1988-09-14 | — | — | EP | disclosed |