Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 5/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854228 | 0.86 | DNMT1 (0.45) | DNMT1ADRB1POLBDNMT3BLMNA | |
| SCHEMBL7644133 | 0.83 | DNMT1 (0.43) | DNMT1ADRB1DNMT3B | |
| SCHEMBL6376811 | 0.82 | DNMT1 (0.51) | DNMT1ADRB1POLBLMNASMN1; SMN2 | |
| SCHEMBL6376815 | 0.82 | DNMT1 (0.51) | DNMT1ADRB1POLBLMNASMN1; SMN2 | |
| SCHEMBL8010181 | 0.80 | DNMT1 (0.53) | DNMT1ADRB1POLBDNMT3BLMNA | |
| SCHEMBL9231567 | 0.80 | DNMT1 (0.53) | DNMT1ADRB1POLBDNMT3BLMNA | |
| SCHEMBL9353594 | 0.77 | DNMT1 (0.55) | DNMT1ADRB1POLBLMNASMN1; SMN2 | |
| SCHEMBL18054787 | 0.77 | DNMT1 (0.59) | DNMT1ADRB1POLBLMNASMN1; SMN2 | |
| SCHEMBL3890489 | 0.77 | DNMT1 (0.59) | DNMT1ADRB1POLBLMNASMN1; SMN2 | |
| SCHEMBL4625691 | 0.77 | DNMT1 (0.59) | DNMT1ADRB1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423839-A2 | Polynucleotides and probes useful in solution phase nucleic acid sandwich assay | CHIRON CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |