SCHEMBL7644133

SCHEMBL7644133

Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)nc1NC(CN)C(=O)CCCCCN

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 5/20 0.43
ADRB1 P08588 1/20 0.43
DNMT3B Q9UBC3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854224 0.83 DNMT1 (0.45) DNMT1ADRB1DNMT3B
SCHEMBL4291160 0.79 DNMT1 (0.55) DNMT1ADRB1
SCHEMBL2584344 0.79 DNMT1 (0.55) DNMT1ADRB1
SCHEMBL5983780 0.77 DNMT1 (0.55) DNMT1ADRB1
SCHEMBL5983784 0.77 DNMT1 (0.55) DNMT1ADRB1
SCHEMBL5983884 0.75 DNMT1 (0.53) DNMT1ADRB1
SCHEMBL5983881 0.75 DNMT1 (0.53) DNMT1ADRB1
SCHEMBL7638345 0.75 DNMT1 (0.40) DNMT1ADRB1DNMT3B
SCHEMBL23119649 0.75 DNMT1 (0.48) DNMT1ADRB1
SCHEMBL21579545 0.75 DNMT1 (0.48) DNMT1ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6465175-B2 REDUCING BACKGROUND SIGNALS IN NUCLEIC ACID HYBRIDIZATION ASSAYS BY USING AN OLIGONUCLEOTIDE LABELLED WITH A QUENCHABLE DIPYRROLOMETHENEBORON DIFLUORIDE DYE BAYER CORPORATION 2002-10-15 US disclosed
US-20010009760-A1 OLIGONUCLEOTIDE PROBES BEARING QUENCHABLE FLUORESCENT LABELS, AND METHODS OF USE THEREOF CHIRON DIAGNOSTICS CORPORATION 2001-07-26 US disclosed
EP-1009852-A2 OLIGONUCLEOTIDE PROBES BEARING QUENCHABLE FLUORESCENT LABELS, AND METHODS OF USE THEREOF Bayer Corporation (US) 2000-06-21 EP disclosed
WO-1999011813-A2 OLIGONUCLEOTIDE PROBES BEARING QUENCHABLE FLUORESCENT LABELS, AND METHODS OF USE THEREOF BAYER CORPORATION (US) 1999-03-11 WO disclosed