SCHEMBL985436

SCHEMBL985436

O=C(Oc1ccc2ccccc2c1)C(Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.56
MEN1 O00255 5/20 0.56
MAPT P10636 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
PKM P14618 1/20 0.48
PTPN7 P35236 1/20 0.47
MMP1 P03956 2/20 0.46
MMP12 P39900 1/20 0.46
FABP7 O15540 1/20 0.45
FABP3 P05413 1/20 0.45
BCHE P06276 1/20 0.45
FAAH O00519 1/20 0.45
EPHX1 P07099 1/20 0.45
MMP2 P08253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30339521 0.81 ELANE (0.58) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL12618375 0.81 ELANE (0.58) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL1896897 0.81 KMT2A (0.56) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL1456652 0.80 ELANE (0.52) KMT2AMEN1TDP1HSD17B10SMN1; SMN2
SCHEMBL6721081 0.79 KMT2A (0.53) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL12128694 0.79 KMT2A (0.53) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL1347890 0.79 KMT2A (0.61) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL1809377 0.78 KMT2A (0.66) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL21881869 0.78 KMT2A (0.66) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL987567 0.78 ELANE (0.47) KMT2AMEN1MAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107179366-B The high-throughput non-targeted screening identification method of organo-chlorine pollutant in a kind of deposit 南京大学 2019-11-05 CN disclosed
CN-107179366-A The non-targeted examination authentication method of organo-chlorine pollutant high flux in a kind of deposit 南京大学 2017-09-19 CN disclosed
US-20160349088-A1 MONITORING DEVICES AND PROCESSES BASED ON TRANSFORMATION, DESTRUCTION AND CONVERSION OF NANOSTRUCTURES PATEL GORDHANBHAI (US) 2016-12-01 US disclosed
EP-2475612-A1 MONITORING DEVICES AND PROCESSES BASED ON TRANSFORMATION, DESTRUCTION AND CONVERSION OF NANOSTRUCTURES JP LABORATORIES, INC. (US) 2012-07-18 EP disclosed
WO-2011031959-A1 MONITORING DEVICES AND PROCESSES BASED ON TRANSFORMATION, DESTRUCTION AND CONVERSION OF NANOSTRUCTURES JP LABORATORIES, INC. (US) 2011-03-17 WO disclosed
US-20110003279-A1 Monitoring devices and processes based on transformation, destruction and conversion of nanostructures PATEL GORDHANBHAI NATHALAL 2011-01-06 US disclosed
EP-0341585-B1 PRODUCTION OF 3,5,6-TRICHLORO-PYRIDIN-2-OL AND NOVEL INTERMEDIATES THEREOF LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1993-01-13 EP disclosed
US-5017705-A Production of 3,5,6-trichloropyridin-2 ol and novel intermediates thereof LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1991-05-21 US disclosed
EP-0341585-A1 Production of 3,5,6-trichloro-pyridin-2-ol and novel intermediates thereof LUXEMBOURG INDUSTRIES (PAMOL) LTD. (IL) 1989-11-15 EP disclosed